Microfluidic Devices Manufacturing

Our MICROFLUIDIC DEVICES MANUFACTURING operations okuhloswe ngayo ukwenziwa kwamadivayisi amancane namasistimu okuwuketshezi oluncane Sinekhono lokukudizayinela amadivaysi e-microfluidic futhi sikunikeze i-prototyping & micromanufacturing ngokwezifiso ezenzelwe izinhlelo zakho zokusebenza. Izibonelo zamadivayisi e-microfluidic amadivaysi e-micro-propulsion, amasistimu e-lab-on-a-chip, ama-micro-thermal devices, ama-inkjet printheads nokuningi. In MICROFLUIDICS kufanele sibhekane nokulawula okunembayo kanye nokuxhashazwa koketshezi olukhawulelwe esifundeni esingamamitha angaphansi. Uketshezi luyanyakaziswa, luxutshwe, luhlukaniswe futhi lucutshungulwe. Kuzinhlelo ze-microfluidic uketshezi luyanyakaziswa futhi lulawuleke ngokusebenzisa amaphampu amancane amancane nama-microvalve nokunye okunjalo noma ngokungenzi lutho kusetshenziswa amandla e-capillary. Ngezinhlelo ze-lab-on-a-chip, izinqubo ezivame ukwenziwa elebhu zenziwa zibe mincane ku-chip eyodwa ukuze kuthuthukiswe ukusebenza kahle nokuhamba kanye nokunciphisa amasampula namavolumu ezinto ezisebenzayo.

 

Ezinye izinhlelo zokusebenza ezinkulu zamadivayisi nezinhlelo ze-microfluidic yilezi:

 

 

 

- Laboratories on a chip

 

- Ukuhlolwa kwezidakamizwa

 

- Ukuhlolwa kweglucose

 

- Chemical microreactor

 

- Ukupholisa i-Microprocessor

 

- Micro fuel cell

 

- Amaprotheni crystallization

 

- Izidakamizwa ezisheshayo ziyashintsha, ukuxhaphazwa kwamangqamuzana angawodwa

 

- Izifundo zeseli eyodwa

 

- Ama-optofluidic microlens arrays asebenzayo

 

- Amasistimu we-Microhydraulic kanye ne-micropneumatic (amaphampu anguketshezi, ama-valve egesi, amasistimu okuxuba ... njll)

 

- Izinhlelo zokuxwayisa ze-Biochip kusenesikhathi

 

- Ukutholwa kwezinhlobo zamakhemikhali

 

- Izicelo ze-Bioanalytical

 

- Ku-chip DNA kanye nokuhlaziywa kwamaprotheni

 

- Imishini yokufutha yeNozzle

 

- I-Quartz flow cell ukuze kutholakale amagciwane

 

- Ama-chips okukhiqiza amaconsi amabili noma amaningi

 

 

 

Onjiniyela bethu abaklami banesipiliyoni seminyaka eminingi ekumodeleni, ekudizayineni nasekuhloleni amadivaysi e-microfluidic ezinhlobonhlobo zezinhlelo zokusebenza. Ubuchwepheshe bethu bokuklama endaweni ye-microfluidics buhlanganisa:

 

 

 

• Inqubo ye-thermal bonding esezingeni eliphansi ye-microfluidics

 

• Ukucwiliswa okumanzi kwamashaneli amancane anokujula kwe-nm kuya ku-mm ejulile engilazini kanye ne-borosilicate.

 

• Ukugaya nokupholishwa kobubanzi obuhlukahlukene be-substrate ukusuka kokuncane okungama-microns ayi-100 kuye kwangaphezu kuka-40 mm.

 

• Ikhono lokuhlanganisa izendlalelo eziningi ukuze udale amadivaysi e-microfluidic ayinkimbinkimbi.

 

• Amasu okubhoboza, ukudayela kanye nama-ultrasonic machining afanele amadivaysi e-microfluidic

 

• Amasu amasha okudayela anoxhumo olunembile lokuxhumanisa amadivaysi e-microfluidic

 

• Ukuqondanisa okunembile

 

• Izinhlobonhlobo zama-coatings adiphozithiwe, ama-microfluidic chips angafafazwa ngezinsimbi ezifana neplatinamu, igolide, ithusi ne-titanium ukuze kwakheke inhlobonhlobo yezici, njengama-RTD ashumekiwe, izinzwa, izibuko nama-electrode.

 

 

 

Ngaphandle kwamakhono ethu okwakha ngokwezifiso sinamakhulu emiklamo ye-microfluidic chip ejwayelekile engekho eshalofini etholakala nge-hydrophobic, i-hydrophilic noma i-fluorinated coatings kanye nohlu olubanzi lwamasayizi wesiteshi (ama-nanometer angu-100 kuya ku-1mm), okokufaka, okuphumayo, amajiyometri ahlukene njengesiphambano esiyindilinga. , izinsika ezifana ne-micromixer. Imishini yethu ye-microfluidic inikeza ukumelana kwamakhemikhali okuhle kakhulu nokubonakala obala, izinga lokushisa eliphezulu elizinzile lifika ku-500 Centigrade, ingcindezi ephezulu ifinyelela ku-300 Bar. Amanye ama-microfluidic off-shelf chips adumile yilawa:

 

 

 

I-MICROFLUIDIC DROPLET CHIPS: Ama-Chips e-Glass Droplet anamajometri ahlukene okuhlangana, osayizi besiteshi kanye nezakhiwo ezingaphezulu ziyatholakala. I-Microfluidic droplet chips inokucaca okuhle kakhulu kokubona isithombe esicacile. Ukwelashwa okuthuthukisiwe kwe-hydrophobic coating kwenza amaconsi amanzi angaphakathi kuwoyela akhiqizwe kanye namaconsi kawoyela emanzini akhiwe kuma-chips angakahlanzwa.

 

I-MICROFLUIDIC MIXER CHIPS: Ivumela ukuxutshwa kokugeleza koketshezi okubili phakathi kwama-millisecond, ama-micromixer chips azuza izinhlobonhlobo zezinhlelo zokusebenza ezihlanganisa i-reaction kinetics, ukuhlanjululwa kwesampula, ukucwebezela okusheshayo kanye nokuhlanganiswa kwe-nanoparticle.

 

I-SINGLE MICROFLUIDIC CHANNEL CHIPS: I-AGS-TECH Inc. inikeza ama-microfluidic esiteshi esisodwa esine-inlet eyodwa kanye ne-outlet eyodwa yezinhlelo zokusebenza ezimbalwa. Izinhlobo ezimbili zama-chip ezihlukene ziyatholakala ngaphandle kweshalofu (66x33mm kanye no-45x15mm). Siphinde sibeke izibambi zama-chip ezihambisanayo.

 

I-CROSS MICROFLUIDIC CHANNEL CHIPS: Siphinde sinikeze ama-microfluidic chips anamashaneli amabili alula awelanayo. Ilungele ukukhiqizwa kwamaconsi kanye nezinhlelo zokusebenza ezigxile ekugelezeni. Ubukhulu be-chip obujwayelekile bungu-45x15mm futhi sinesibambi se-chip esihambisanayo.

 

I-T-JUNCTION CHIPS: I-T-Junction iyijiyomethri eyisisekelo esetshenziswa kuma-microfluidics okuxhumana okuwuketshezi kanye nokwakheka kwamaconsi. Lawa ma-microfluidic chips atholakala ngenani lezinhlobo ezihlanganisa ungqimba oluncane, i-quartz, i-platinum coated, izinguqulo ze-hydrophobic kanye ne-hydrophilic.

 

I-Y-JUNCTION CHIPS: Lawa ngamadivayisi engilazi amancane adizayinelwe uhla olubanzi lwezinhlelo zokusebenza ezihlanganisa ukuxhumana noketshezi oluwuketshezi kanye nezifundo zokusabalalisa. Lawa madivayisi we-microfluidic afaka ama-Y-Junctions amabili axhunyiwe kanye namashaneli amabili aqondile okubuka ukugeleza kwe-microchannel.

 

I-MICROFLUIDIC REACTOR CHIPS: Ama-Microreactor chips angamadivayisi amancane engilazi ahlangene aklanyelwe ukuxubana okusheshayo nokusabela kokugeleza kwe-agent ewuketshezi emibili noma emithathu.

 

WELLPLATE CHIPS: Leli ithuluzi locwaningo lokuhlaziya kanye namalabhorethri okuxilonga emitholampilo. Ama-Wellplate chips awokugcina amaconsi amancane ama-reagents noma amaqembu amaseli emithonjeni ye-nano-litre.

 

AMADIVAYISI E-MEMBRANE: Lawa madivayisi we-membrane aklanyelwe ukusetshenziselwa ukuhlukanisa uketshezi oluwuketshezi, ukuthintana noma ukukhipha, ukuhlungwa kokugeleza okuwela kanye nokusabela kwamakhemikhali angaphezulu. Lawa madivaysi azuza kuvolumu efile ephansi kanye nolwelwesi olulahlwayo.

 

I-MICROFLUIDIC RESEALABLE CHIPS: Idizayinelwe ama-microfluidic chips angavulwa futhi aphinde avale, ama-chips avalekayo anika amandla kufikela kuxhumano lukagesi oluyi-fluidic kanye nesishiyagalombili kanye nokubekwa kwezinto ezivuselelayo, izinzwa noma amaseli endaweni yesiteshi. Ezinye izinhlelo zokusebenza isiko lamaseli nokuhlaziya, ukutholwa kokungena kwe-impedance kanye nokuhlolwa kwe-biosensor.

 

I-POROUS MEDIA CHIPS: Lena idivayisi yengilazi encane edizayinelwe ukumodela ngezibalo kwesakhiwo setshe le-sandstone eliyinkimbinkimbi. Phakathi kwezicelo zale chip microfluidic ucwaningo lwesayensi yomhlaba nobunjiniyela, imboni ye-petrochemical, ukuhlolwa kwemvelo, ukuhlaziywa kwamanzi angaphansi komhlaba.

 

I-CAPILLARY ELECTROPHORESIS CHIP (I-chip ye-CE): Sinikeza ama-capillary electrophoresis chips anama-electrode ahlanganisiwe nangenawo okuhlaziya i-DNA nokuhlukaniswa kwama-biomolecules. Ama-chips e-Capillary electrophoresis ahambisana ne-encapsulates yobukhulu obungu-45x15mm. Sinama-CE chips eyodwa ene-classical crossing kanye ne-T-crossing.

 

Zonke izesekeli ezidingekayo njengezibambi zama-chip, izixhumi ziyatholakala.

 

 

 

Ngaphandle kwama-microfluidic chips, i-AGS-TECH inikeza anhlobonhlobo amaphampu, amashubhu, amasistimu ama-microfluidic, izixhumi nezinye izinto. Amanye amasistimu we-microfluidic angekho eshalofini yilawa:

 

 

 

I-MICROFLUIDIC DROPLET Starter SYSTEMS: Uhlelo lwe-droplet starter olusekelwe kwisirinji luhlinzeka ngesixazululo esiphelele sokukhiqizwa kwamaconsi ahlakazekile asukela kububanzi obuyi-micron ayi-10 kuye kwangama-250. Isebenza kububanzi bokugeleza okubanzi phakathi kuka-0.1 microliter/min kuya ku-10 microliter/min, isistimu ye-microfluidics emelana namakhemikhali ilungele umsebenzi womqondo wokuqala nokuhlola. Ngakolunye uhlangothi uhlelo lwe-droplet starter olusekelwe kungcindezi luyithuluzi lomsebenzi wokuqala kuma-microfluidics. Uhlelo luhlinzeka ngesixazululo esiphelele esiqukethe wonke amaphampu adingekayo, izixhumi nama-chips microfluidic avumela ukukhiqizwa kwamaconsi ahlakazeke kakhulu asuka ku-10 kuya ku-150 microns. Isebenza ngengcindezi ebangeni elibanzi eliphakathi kwamabha angu-0 kuye kwayi-10, le sistimu imelana ngamakhemikhali futhi ukwakheka kwayo kwe-modular kuyenza ikhuliseke kalula ezinhlelweni zokusebenza ezizayo. Ngokuhlinzeka ngokugeleza koketshezi okuzinzile, le khithi yamathuluzi eyimojula isusa umthamo ofile kanye nodoti wesampula ukuze kuncishiswe ngempumelelo izindleko ze-reagent ehlobene. Lolu hlelo lwe-microfluidic lunikeza ikhono lokuhlinzeka ngokushintsha koketshezi olusheshayo. Igumbi lokucindezela elikhiywayo kanye nesivalo segumbi lezindlela ezi-3 sivumela ukumpompa kanyekanye uketshezi olungafika kokuthathu.

 

 

 

UHLELO LWE-MICROFLUIDIC DROPLET Ethuthukisiwe: Isistimu ye-microfluidic modular evumela ukukhiqizwa kwamaconsi anosayizi ongashintshi, izinhlayiya, ama-emulsion, namabhamuza. Uhlelo oluthuthukisiwe lwe-microfluidic droplet lusebenzisa ubuchwepheshe obugxile ekugelezeni ku-microfluidic chip enokugeleza koketshezi okungenamoya ukuze kukhiqizwe amaconsi ahlakazekile phakathi kwama-nanometer namakhulu osayizi wama-microns. Ifaneleka kahle i-encapsulation yamaseli, ukukhiqiza ubuhlalu, ukulawula ukwakheka kwe-nanoparticle njll. Usayizi we-Droplet, amazinga okugeleza, amazinga okushisa, ukuhlangana kokuxuba, izakhiwo ezingaphezulu kanye nokuhleleka kwezengezo kungahlukahluka ngokushesha ukuze kusetshenziswe inqubo. Uhlelo lwe-microfluidic luqukethe zonke izingxenye ezidingekayo ezihlanganisa amaphampu, izinzwa zokugeleza, ama-chips, izixhumi nezingxenye ezishintshayo. Izesekeli nazo ziyatholakala, okuhlanganisa amasistimu okubona, amachibi amakhudlwana kanye nama-reagent kits. Ezinye izinhlelo zokusebenza ze-microfluidics zalolu hlelo ukuhlanganisa amangqamuzana, i-DNA kanye nobuhlalu kazibuthe ukuze kwenziwe ucwaningo nokuhlaziya, ukulethwa kwezidakamizwa ngezinhlayiya ze-polymer nokwakhiwa kwezidakamizwa, ukukhiqizwa okunembayo kwama-emulsion namagwebu okudla nezimonyo, ukukhiqizwa kwamapende nezinhlayiya ze-polymer, ucwaningo lwe-microfluidics amaconsi, ama-emulsions, amagwebu kanye nezinhlayiya.

 

 

 

UHLELO LWE-MICROFLUIDIC SMALL DROPLET SYSTEM: Uhlelo olufanele lokukhiqiza nokuhlaziya ama-microemulsions anikeza ukuzinza okwengeziwe, indawo ephakeme enobuso kanye namandla okunyibilikisa kokubili izinhlanganisela ezinamanzi nezincibilika uwoyela. Ama-chips amancane we-droplet microfluidic avumela ukukhiqizwa kwamaconsi amancane ahlakazeke kakhulu ukusuka kuma-microns angu-5 ukuya kwangu-30.

 

 

 

I-MICROFLUIDIC PARALLEL DROPLET SYSTEM: Uhlelo lokuphuma okuphezulu lokukhiqiza ama-microdroplets angama-30,000 ahlakazekile ngomzuzwana asuka kuma-microns angama-20 kuye kwangama-60. Uhlelo lwe-microfluidic parallel droplet luvumela abasebenzisi ukuthi bakhe amaconsi azinzile emanzini ku-oyela noma amaconsi kawoyela emanzini asiza uhla olubanzi lwezinhlelo zokusebenza ekukhiqizweni kwezidakamizwa nokudla.

 

 

 

UHLELO LOKUQOQA I-MICROFLUIDIC DROPLET: Lolu hlelo lufaneleka kahle ukukhiqizwa, ukuqoqwa nokuhlaziywa kwama-emulsion ahlakazekile. Isistimu yokuqoqa amaconsi e-microfluidic ihlanganisa imojula yokuqoqwa kwamaconsi evumela ama-emulsion ukuthi aqoqwe ngaphandle kokuphazamiseka kokugeleza noma ukuhlangana kwamaconsi. Usayizi we-microfluidic droplet ungalungiswa ngokunembile futhi ushintshwe ngokushesha okuvumela ukulawula okugcwele izici ze-emulsion.

 

 

 

I-MICROFLUIDIC MICROMIXER SYSTEM: Lolu hlelo lwenziwe ngedivayisi ye-microfluidic, ukupompa okunembayo, izakhi ze-microfluidic kanye nesofthiwe ukuze kutholwe ukuxubana okuhle kakhulu. Idivaysi encane yengilazi ye-microfluidic esekwe ku-lamination ivumela ukuxutshwa okusheshayo kwemifudlana yoketshezi emibili noma emithathu kujometri exubene ngayinye kwezimbili ezizimele. Ukuxuba okuphelele kungafinyelelwa ngale divayisi ye-microfluidic kukho kokubili izilinganiso zokugeleza okuphezulu nokuphansi. Idivayisi ye-microfluidic, kanye nezingxenye zayo ezizungezile zinikeza ukuqina okuhle kakhulu kwamakhemikhali, ukubonakala okuphezulu kwe-optics, kanye nokudluliswa okuhle kokubona. Isistimu ye-micromixer isebenza ngokushesha okukhulu, isebenza kumodi yokugeleza eqhubekayo futhi ingaxuba ngokuphelele imifudlana yoketshezi emibili noma emithathu phakathi kwama-millisecond. Ezinye izinhlelo zokusebenza zale divayisi yokuxuba ye-microfluidic i-reaction kinetics, i-dilution yesampula, ukukhetha okuthuthukisiwe kokusabela, i-crystallization esheshayo kanye ne-nanoparticle synthesis, ukusebenza kweseli, ukusabela kwe-enzyme kanye ne-DNA hybridization.

 

 

 

I-MICROFLUIDIC DROPLET-ON-DEMAND SYSTEM: Lolu uhlelo oluncane lwe-droplet-on-demand microfluidic oluhlangene futhi oluphathekayo lokukhiqiza amaconsi amasampula ahlukene angama-24 futhi lugcine amaconsi afika kwangu-1000 anosayizi abafika kuma-nanoliter angama-25. Uhlelo lwe-microfluidic lunikeza ukulawula okuhle kakhulu kosayizi wamaconsi kanye nemvamisa kanye nokuvumela ukusetshenziswa kwama-reagents amaningi ukudala ama-assay ayinkimbinkimbi ngokushesha futhi kalula. Amaconsi e-Microfluidic angagcinwa, ahanjiswe ngebhayisikili ngokushisa, ahlanganiswe noma ahlukaniswe kusuka kumaconsi e-nanoliter kuya kumaconsi e-picoliter. Ezinye izinhlelo zokusebenza yilezi, ukukhiqizwa kwemitapo yolwazi yokuhlola, ukufakwa kwamaseli, ukuhlanganisa izinto eziphilayo, ukuzenzekelayo kokuhlolwa kwe-ELISA, ukulungiswa kwama-concentration gradients, i-combinatorial chemistry, ukuhlolwa kwamaseli.

 

 

 

UHLELO LWE-NANOPARTICLE SYNTHESIS: Ama-Nanoparticles mancane kune-100nm futhi azuzisa uhla lwezinhlelo zokusebenza ezifana nokuhlanganiswa kwe-silicon esekelwe ku-fluorescent nanoparticles (amachashazi we-quantum) ukuze alebule ama-biomolecules ngezinjongo zokuxilonga, ukulethwa kwezidakamizwa, nokuthwebula kweselula. Ubuchwepheshe be-Microfluidics bulungele ukuhlanganiswa kwe-nanoparticle. Ukunciphisa ukusetshenziswa kwe-reagent, kuvumela ukusatshalaliswa kosayizi wezinhlayiyana okuqinile, ukulawula okuthuthukisiwe ezikhathini zokusabela namazinga okushisa, kanye nokusebenza kahle kokuxuba.

 

 

 

UHLELO LOKWENZIWA KWE-MICROFLUIDIC DROPLET: Uhlelo olusezingeni eliphezulu lwe-microfluidic olusiza ukukhiqizwa okungafika kuthani lamaconsi ahlakazeke kakhulu, izinhlayiya noma i-emulsion ngenyanga. Lolu hlelo lwe-microfluidic olumodulayo, olunwebekayo futhi oluguquguquka kakhulu luvumela amamojula angafika kwayi-10 ukuthi ahlanganiswe ngokuhambisana, okuvumela izimo ezifanayo kuze kufike ku-70 microfluidic chip droplet junctions. Ukukhiqizwa ngobuningi kwamaconsi amancane ahlakazeke kakhulu asukela phakathi kwama-microns angu-20 kanye nama-microns angu-150 kungenzeka angageleza asuke kuma-chips, noma angene kumashubhu. Izicelo zihlanganisa ukukhiqizwa kwezinhlayiyana - i-PLGA, i-gelatin, i-alginate, i-polystyrene, i-agarose, ukulethwa kwezidakamizwa ngokhilimu, ama-aerosol, ukukhiqizwa kwenqwaba yama-emulsion namagwebu ekudleni, izimonyo, izimboni zikapende, ukuhlanganiswa kwe-nanoparticle, ukuxutshwa kwe-micromixing okuhambisanayo kanye nokusabela okuncane.

 

 

 

UHLELO LOKULAWULA UKUFAKAZA KWAMA-MICROFLUIDIC ECRESSURE-DRIVEN MICROFLUIDIC: Ukulawulwa kokugeleza okuhlakaniphile okuvaliwe kunikeza ukulawula amazinga okugeleza ukusuka ku-nanoliter/min ukuya kumamililitha/min, ngezingcindezi ezisuka kumabha ayi-10 wehle kuye ku-vacuum. Inzwa yesilinganiso sokugeleza exhunywe emgqeni phakathi kwephampu kanye nedivayisi ye-microfluidic isiza abasebenzisi ukuthi bafake umgomo wesilinganiso sokugeleza ngokuqondile kupompo ngaphandle kwesidingo se-PC. Abasebenzisi bazothola ukushelela kwengcindezi nokuphindaphinda kokugeleza kwevolumu kumadivayisi wabo we-microfluidic. Amasistimu anganwetshwa kumaphampu amaningi, azolawula izinga lokugeleza ngokuzimela. Ukuze usebenze kumodi yokulawula ukugeleza, inzwa yezinga lokugeleza idinga ukuxhunywa kupompo kusetshenziswa isibonisi senzwa noma isixhumi esibonakalayo senzwa.